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Guides

What living on a GLP-1 actually involves

Side effects, food, injections, travel and the questions worth asking — written from the prescribing information and the published trials, with every figure linked to where it came from. None of it is medical advice, and none of it tells you what to do with a dose.

39 guides · Updated

Life on a GLP-1

Holidays, work, dating, telling people, moving more, food on a small appetite and progress beyond the scale.

Read the life guides

Side effects

What the labels report, how common each effect was in the trials, and when a symptom is a reason to call someone.

  • GLP-1 side effects: the complete guide

    Every common reaction with the trial rates from the labels, the serious warnings, and what changed in 2026.

  • When side effects start and how long they last

    Why side effects follow the dose more than the calendar, the dose-day rhythm, and when not to wait.

  • Nausea

    The most common side effect: how often it was reported, why it happens, what helps and when to call someone.

  • Constipation

    Why a slower gut causes it, what the 2025 nutrition advisory suggests, and the rare signs that are urgent.

  • Diarrhoea

    How common it is, why fluids come first, and the signs that need a clinician.

  • Heartburn, reflux and indigestion

    Why a slower stomach brings them on, what helps, and the symptoms that need a doctor.

  • Burping and sulphur burps

    How often burping was reported, why it can smell of sulphur on a slower gut, and what helps.

  • Tiredness

    Why fatigue is common in the first weeks, what feeds it, and when to get it checked.

  • Headaches

    How much more common they are than on placebo, the likely contributors, and the red flags.

  • Bloating and wind

    Why a slower gut brings them on, what helps, and the signs of something more serious.

  • Dizziness

    The link with blood pressure, fluids and blood sugar, and when dizziness needs a clinician.

  • Hair loss

    How common it is, why the labels link it to weight loss, and what is known about regrowth.

  • Tingling or sensitive skin

    Dysaesthesia: why it is linked to higher semaglutide doses and what the label reports.

  • Mood

    What the FDA concluded in 2026, what the labels report now, and where to get help.

  • Sleep

    Insomnia, night-time reflux, and tirzepatide's approval for obstructive sleep apnoea.

Eating and drinking

Protein, fibre, water and appetite — the parts of the day a smaller appetite changes most.

  • What to eat on a GLP-1

    The 2025 joint advisory in plain English: protein first, fibre, fluids, micronutrients and eating around side effects.

  • What to eat on injection day

    What the labels say about food and timing, why the tablets differ, and a practical plan for shot day.

  • Eating with no appetite

    Eating by the clock, easy protein for low days, and when too little becomes a problem.

  • Food noise

    What it means, why it goes quiet on a GLP-1, why it can return late in the week, and how to track it.

  • Hydration and electrolytes

    Why the labels stress fluids, how much the reference intakes suggest, and when electrolytes help.

  • Alcohol

    Why it can worsen side effects, the low blood sugar risk, and what the craving research found.

  • Eating out

    Ordering for the stomach you have now: smaller, protein first, lighter cooking.

Living with it

Injection sites, travel, the first weeks, plateaus and stopping.

The medicines

What the GLP-1 medicines are and how they differ, by generic name.

Appointments

Getting the most from the time you have with a prescriber.