Guides
What living on a GLP-1 actually involves
Side effects, food, injections, travel and the questions worth asking — written from the prescribing information and the published trials, with every figure linked to where it came from. None of it is medical advice, and none of it tells you what to do with a dose.
39 guides · Updated
Life on a GLP-1
Holidays, work, dating, telling people, moving more, food on a small appetite and progress beyond the scale.
Side effects
What the labels report, how common each effect was in the trials, and when a symptom is a reason to call someone.
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GLP-1 side effects: the complete guide
Every common reaction with the trial rates from the labels, the serious warnings, and what changed in 2026.
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When side effects start and how long they last
Why side effects follow the dose more than the calendar, the dose-day rhythm, and when not to wait.
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Nausea
The most common side effect: how often it was reported, why it happens, what helps and when to call someone.
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Constipation
Why a slower gut causes it, what the 2025 nutrition advisory suggests, and the rare signs that are urgent.
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Diarrhoea
How common it is, why fluids come first, and the signs that need a clinician.
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Heartburn, reflux and indigestion
Why a slower stomach brings them on, what helps, and the symptoms that need a doctor.
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Burping and sulphur burps
How often burping was reported, why it can smell of sulphur on a slower gut, and what helps.
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Tiredness
Why fatigue is common in the first weeks, what feeds it, and when to get it checked.
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Headaches
How much more common they are than on placebo, the likely contributors, and the red flags.
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Bloating and wind
Why a slower gut brings them on, what helps, and the signs of something more serious.
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Dizziness
The link with blood pressure, fluids and blood sugar, and when dizziness needs a clinician.
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Hair loss
How common it is, why the labels link it to weight loss, and what is known about regrowth.
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Tingling or sensitive skin
Dysaesthesia: why it is linked to higher semaglutide doses and what the label reports.
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Mood
What the FDA concluded in 2026, what the labels report now, and where to get help.
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Sleep
Insomnia, night-time reflux, and tirzepatide's approval for obstructive sleep apnoea.
Eating and drinking
Protein, fibre, water and appetite — the parts of the day a smaller appetite changes most.
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What to eat on a GLP-1
The 2025 joint advisory in plain English: protein first, fibre, fluids, micronutrients and eating around side effects.
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What to eat on injection day
What the labels say about food and timing, why the tablets differ, and a practical plan for shot day.
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Eating with no appetite
Eating by the clock, easy protein for low days, and when too little becomes a problem.
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Food noise
What it means, why it goes quiet on a GLP-1, why it can return late in the week, and how to track it.
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Hydration and electrolytes
Why the labels stress fluids, how much the reference intakes suggest, and when electrolytes help.
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Alcohol
Why it can worsen side effects, the low blood sugar risk, and what the craving research found.
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Eating out
Ordering for the stomach you have now: smaller, protein first, lighter cooking.
Living with it
Injection sites, travel, the first weeks, plateaus and stopping.
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Your first month
The building-up weeks, early side effects, and what to set up from day one.
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Injection-site reactions
Redness, bruises and lumps: how common they are, rotating sites, and skin to avoid.
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Travelling with a GLP-1
Storage limits from each label, airport security, and what to ask about dose day abroad.
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Weight-loss plateaus
Why weight loss slows, when it flattened in the trials, and how to tell a plateau from daily noise.
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Muscle loss and strength
What the body-composition scans show, and the protein and strength-training guidance.
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Stopping a GLP-1
What the stopping trials found, how the medicine clears, and what to plan with your prescriber.
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Contraception, pregnancy and breastfeeding
Birth control pills, planning a pregnancy and breastfeeding — what each label says.
The medicines
What the GLP-1 medicines are and how they differ, by generic name.
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The GLP-1 medicines explained
Six medicines by generic name: how each is taken, how long it lasts, and what it is approved for.
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Semaglutide vs tirzepatide
How they differ, the SURMOUNT-5 head-to-head trial, and side effects from the labels.
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How long semaglutide stays in your system
A one-week half-life, 5 to 7 weeks to clear, and what that means day by day.
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How long tirzepatide stays in your system
A 5-to-6-day half-life, about a month to clear, and the larger swing within each week.
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Liraglutide vs semaglutide
Daily versus weekly, and the STEP 8 head-to-head result.
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Pills and injections
Oral semaglutide and orforglipron versus weekly injections: routine, results, storage.
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Compounded GLP-1s
What they are, what the FDA has said, and how to keep a safe record.
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GLP-1 glossary
45 terms from labels, trials and the pharmacy, explained plainly.
Appointments
Getting the most from the time you have with a prescriber.
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Questions to ask your doctor
What the labels ask you to tell your prescriber, and the questions worth asking back. Printable checklist.
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Records for insurance renewals
What a US prior authorization renewal may ask for, and the record that answers it.